February 17, 2019

Granulosis rubra nasi is a rare condition characterised by hyperhidrosis of the nose. Granulosis Rubra Nasi (GRN) is a rare disorder of the eccrine glands. It is clinically characterized by hyperhidrosis of the central part of the face. Granulosis rubra nasi is a rare familial disease of children, occurring on the nose, cheeks, and chin, characterized by diffuse redness, persistent excessive.

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In the case of perioral dermatitis there are small monomorphic papules, pustules, erythema, and scaling involving the perioral area and no hyperhidrosis.

However, erythema over the central face was persisting. It is commonly seen in childhood, but can also occur in adults. Case Reports in Dermatological Medicine.

As a result of persistent hyperhidrosis, diffuse erythema develops over the tip of the nose. This page was last edited on 22 Julyat Perioral dermatitis can present with erythema, small monomorphic papules, and pustules with or without scaling involving the perioral area without hyperhidrosis. Patient had noticed decreased sweating over the area, once vesicles started to appear. Based on clinical presentation and histopathology, diagnosis of Granulosis rubra nasi GRN was made.

Topical indomethacin, drying lotions like calamine, tetracycline, cryotherapy, and X-rays temporary benefit have been described in the treatment of GRN [ 13 ].


Granulosis rubra nasi

Diseases of the eccrine and apocrine sweat glands. Shows erythema more prominently. The skin biopsy showed dilatation of blood vessels, dilated sweat ducts with a discrete mononuclear cell infiltrate surrounding them [ Figure 3 ].

However, in some cases it may persist in adulthood. This chapter is set out as follows: The differential diagnosis includes rosacea nxsi perioral dermatitis.

Granulosis rubra nasi – Wikipedia

Clinically, we made a diagnosis of Granulosis Rubra Nasi, Lymphangioma Circumscriptum, Nevus Comedonicus, and sebaceous gland hyperplasia. In next 4—5 years, papular lesions stopped appearing. Our patient presented with granulosis rubra nasi, a rare disease.

Views Read Edit View history. View at Google Scholar E. Presence of significant increase in sweating on the nose and central face appears to be responsible for the secondary changes like erythema and erythematous papules [ 9 ].

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3. A provisional diagnosis of Granulosis rubra nasi was made, and hidrocystoma and rosacea were considered as differential diagnosis.

Correspondence should be addressed to Farhana Tahseen Taj ; moc. Nil Conflict of Interest: He was granjlosis well and there was no relevant family history.

Case Reports in Dermatological Medicine

Please click on images to enlarge or download. Abstract A 20 years-old girl presented with multiple asymptomatic reddish vesicles on face branulosis four years. GRN is an inflammatory condition involving eccrine sweat glands of nose, cheeks and chin. It may also affect the eyebrow, upper lip, and cheek. Patient was counseled regarding the disease and poor response to treatment. Papillary dermis shows dilated capillaries with extravasation of hemosiderin Figure ansi. Rosacea can be differentiated by accentuation of the erythema by vasomotor instability, which is not a feature of GRN.


It used to get worse in summer and was associated with localized hyperhidrosis. Rook’s textbook of dermatology. View at Google Scholar O. Please review our privacy policy. This case is being reported for its rarity since to rubrq best of our knowledge, it has not been reported in Indian subjects so far. Perioral dermatitis Granulomatous perioral dermatitis Phymatous rosacea Rhinophyma Blepharophyma Gnathophyma Metophyma Otophyma Papulopustular rosacea Lupoid rosacea Erythrotelangiectatic rosacea Glandular rosacea Gram-negative rosacea Steroid rosacea Ocular rosacea Persistent edema of rosacea Rosacea conglobata variants Granulosid dermatitis Pyoderma faciale.

New lesions kept appearing.

This article has been cited by other articles in PMC. Proc R Soc Med.