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Design and dm of locked nucleic acid-based splice-switching oligonucleotides in vitro. I agree to the terms and conditions. Sign In or Create an Account. In some strains of Saccharomyces cerevisiae the mitochondrial gene coding for 21S rRNA is interrupted by an intron of bp.

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Abstract In some strains of Saccharomyces cerevisiae the mitochondrial gene coding for 21S rRNA is interrupted by an intron of bp. Close mobile search navigation Article navigation. Your comment will be reviewed and published at the journal’s discretion. Thank you for submitting a comment on this article. Citing articles via Web of Science Get in Touch with us Right Move Consulting.


If you originally registered with a username please use that to sign in. Get best deals for coconut. Image available on request. Speed Dome Ptz Camera. Email alerts New issue alert. You could not be signed in. This article is also available for rental through DeepDyve. In RNA blotting experiments, using an intron specific hybridisation probe, the same intermediates in splicing are found both in wild type and petite mutant.

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Splicing of many human genes involves sites embedded within introns. Speed Dome Camera in Mumbai.

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This intron contains a reading frame for amino acids: In order to check whether expression of this URF is required for proper splicing of precursors to 21S rRNA, the precision of RNA splicing was analysed in a petite mutant, where no mitochondrial protein synthesis is possible anymore. Sign in via your Institution Sign in. Year of Establishment Raytheon Infrastructure is High-quality source for all your security services and Installation. Get Best Price Request a quote.


Call Send a quick message. Don’t have an account? Sign In Forgot password? H-NS uses an autoinhibitory conformational switch for environment-controlled gene silencing.

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dgm Please check for further notifications by email. It furthers the University’s objective of excellence in research, scholarship, and education by publishing worldwide. Finally the synthetic oligonucleotide hybridises to petite 21S rRNA and its thermal dissociation behaviour is indistinguishable from sbm hybrid formed with wildtype 21S rRNA.

We have devised a new assay to monitor the precision of the splicing event. Related articles in Web of Science Google Scholar. Nature of Business Service Provider. You do not currently have access to this article.

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Number of Employees Upto 10 People. The method is of general application, provided that the sequence of the splice boundaries is known. I agree to the 21w and privacy policy.

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